Previous hypersensitivity to penicillins, cephalosporins or other β-lactam agents. Do not use on penicillin-resistant
Strep pneumoniae. Convulsions may occur in patients w/ impaired renal function or in those receiving high dose. Avoid if infectious mononucleosis is suspected. Concomitant use w/ allopurinol. Prolonged use may result in overgrowth of non-susceptible organisms. Discontinue if feverish generalised erythema associated w/ pustula occurs. Antibiotic-associated colitis. Periodic assessment of organ system functions including renal, hepatic & hematopoietic function is advisable during prolonged therapy. Maintain adequate fluid intake & urinary output in order to reduce possibility of amoxicillin crystalluria. False +ve w/ non-enzymatic methods & Coombs' test. Cross-reactions w/ non-Aspergillus polysaccharides & polyfuranose. Hepatic impairment. Avoid use during pregnancy. Lactation.
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